Definitions for amrinone
am·ri·none

Princeton's WordNetRate this definition:0.0 / 0 votes

1. amrinone, Inocornoun

   a drug (trade name Inocor) used intravenously in heart failure; increases strength of contraction of myocardium

WiktionaryRate this definition:0.0 / 0 votes

1. amrinonenoun

   A type 3 pyridine phosphodiesterase inhibitor used to treat congestive heart failure.

2. amrinonenoun

   Former name for inamrinone (changed in 2000 to avoid confusion with amiodarone).

WikipediaRate this definition:0.0 / 0 votes

1. Amrinone

   Amrinone, also known as inamrinone, and sold as Inocor, is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high-gain calcium induced calcium release (CICR). The positive inotropic effect of amrinone is mediated by the selective enhancement of high-gain CICR, which contributes to the contraction of myocytes by phosphorylation through cAMP dependent protein kinase A (PKA) and Ca2+ calmodulin kinase pathways.

ChatGPTRate this definition:0.0 / 0 votes

1. amrinone

   Amrinone, also known as inamrinone, is a type of drug that helps to reduce the symptoms of heart failure. It works by inhibiting phosphodiesterase-3, an enzyme that is involved in cardiac and vascular muscle contraction. This inhibition leads to an increase in the hearts contraction and dilates the blood vessels, making it easier for the heart to pump blood. It is typically used in cases of severe congestive heart failure when other treatments are not effective.

WikidataRate this definition:0.0 / 0 votes

1. Amrinone

   Amrinone or inamrinone, trade name Inocor, is a pyridine phosphodiesterase 3 inhibitor. It is a drug that may improve the prognosis in patients with congestive heart failure. Amrinone has been shown to increase the contractions initiated in the heart by high gain calcium induced calcium release. The positive inotropic effect of amrinone is mediated by the selective enhancement of high gain CICR which contributes to the contraction of myocytes by phosphorylation through cAMP dependent protein kinase A and Ca2+ calmodulin kinase pathways.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Amrinone

   A positive inotropic cardiotonic (CARDIOTONIC AGENTS) with vasodilator properties, phosphodiesterase inhibitory activity, and the ability to stimulate calcium ion influx into the cardiac cell.

Matched Categories

1. • Medicine

Usage in printed sourcesFrom: 

1. [["1966","1"],["1973","2"],["1974","3"],["1976","7"],["1977","4"],["1978","2"],["1979","61"],["1980","21"],["1981","24"],["1982","206"],["1983","126"],["1984","196"],["1985","160"],["1986","972"],["1987","333"],["1988","368"],["1989","329"],["1990","498"],["1991","778"],["1992","451"],["1993","466"],["1994","723"],["1995","489"],["1996","614"],["1997","544"],["1998","748"],["1999","349"],["2000","457"],["2001","656"],["2002","411"],["2003","220"],["2004","262"],["2005","353"],["2006","247"],["2007","166"],["2008","251"]]

How to pronounce amrinone?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

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   Fred

   US English

   Tessa

   South African

How to say amrinone in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of amrinone in Chaldean Numerology is: 3

2. Pythagorean Numerology

   The numerical value of amrinone in Pythagorean Numerology is: 8

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=amrinone
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Amrinone
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Amrinone
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=amrinone
6. ^ Usage in printed sources
   https://books.google.com/ngrams/graph?content=amrinone