Definitions for amitotic
ami·tot·ic

Princeton's WordNetRate this definition:0.0 / 0 votes

1. amitoticadjective

   pertaining to a simple method of cell division

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1. amitoticadjective

   Of or pertaining to amitosis

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1. amitotic

   Amitosis (a- + mitosis), also called karyostenosis or direct cell division or binary fission, is cell proliferation that does not occur by mitosis, the mechanism usually identified as essential for cell division in eukaryotes. The polyploid macronucleus found in ciliates divides amitotically. While normal mitosis results in a precise division of parental alleles, amitosis results in a random distribution of parental alleles. Ploidy levels of >1000 in some species means both parental alleles can be maintained over many generations, while species with fewer numbers of each chromosome will tend to become homozygous for one or the other parental allele through a process known as phenotypic or allelic assortment. It does not involve maximal condensation of chromatin into chromosomes, observable by light microscopy as they line up in pairs along the metaphase plate. It does not involve these paired structures being pulled in opposite directions by a mitotic spindle to form daughter cells. Rather, it effects nuclear proliferation without the involvement of chromosomes, unsettling for cell biologists who have come to rely on the mitotic figure as reassurance that chromatin is being equally distributed into daughter cells. The phenomenon of amitosis, even though it is an accepted as occurring in ciliates, continues to meet with skepticism about its role in mammalian cell proliferation, perhaps because it lacks the reassuring iconography of mitosis. Of course the relatively recent discovery of copy number variations (CNVs) in mammalian cells within an organ significantly challenges the age-old assumption that every cell in an organism must inherit an exact copy of the parental genome to be functional. Rather than CNVs resulting from mitosis gone awry, some of this variation may arise from amitosis, and may be both desirable and necessary. Furthermore, ciliates possess a mechanism for adjusting copy numbers of individual genes during amitosis of the macronucleus.Amitosis was first described in 1880 by Walther Flemming (more celebrated for describing mitosis) and others (Child, 1907). For a few years thereafter, it was common for biologists to think cells sometimes divided by mitosis but at other times could divide by amitosis. However, since the turn of the twentieth century, amitosis has not received much attention. Using "mitosis in mammalian cells" as a search term in the Medline data-base calls up more than 10,000 studies dealing with mitosis, whereas "amitosis in mammalian cells" retrieves the titles of fewer than 50 papers. This absence of data has led many scientists to conclude that amitosis does not exist, or is minimally important—if any means of proliferation can be deemed "minimally important" while the war on cancer is not yet won. Accordingly, a resurgence of interest in the role of amitosis in mammalian proliferation has been building over the past two to three decades. A review of the resulting literature not only affirms the involvement of amitosis in cell proliferation, it also explores the existence of more than one amitotic mechanism capable of producing "progeny nuclei" without the involvement of "mitotic chromosomes." One form of amitosis involves fissioning, a nucleus splitting in two without the involvement of chromosomes, and has been reported in placental tissue as well as in cells grown from that tissue in rats, in human trophoblasts, and in mouse trophoblasts. Amitosis by fissioning has also been reported in mammalian liver cells and human adrenal cells. Chen and Wan not only reported amitosis in rat liver, but also presented a mechanism for a four-stage amitotic process whereby chromatin threads are reproduced and equally distributed to daughter cells as the nucleus splits in two. Additional examples of non-mitotic proliferation, and important insights into underlying mechanisms, have resulted from extensive work with polyploid cells. Such cells, long acknowledged to exist, were once believed simply to be anomalous. Accumulating research, including in the liver now suggests that cells containing multiple copies of the genome are importantly involved in a cell's ability to adapt to its environment. A couple of decades of research has shown that polyploid cells are frequently "reduced" to diploid cells by amitosis (Zybina et al.). For instance, naturally occurring polyploid placental cells have been shown capable of producing nuclei with diploid or near-diploid complements of DNA. Furthermore, Zybina and her colleagues have demonstrated that such nuclei, derived from polyploid placental cells, receive one or more copies of a microscopically identifiable region of the chromatin, demonstrating that even without the reassuring iconography of identical chromosomes being distributed into "identical" daughter cells, this particular amitotic process results in representative transmission of chromatin. Studying rat polyploid trophoblasts, this research group has shown that the nuclear envelope of th

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1. amitotic

   Amitotic refers to a type of cell division where the nucleus and cytoplasm divide by constriction without the formation of chromosomes or the occurrence of mitosis. This process happens predominantly in some lower forms of life such as bacteria, protozoans, and algae. In higher organisms, amitosis is observed in tissues that typically do not divide, like mature cardiac muscle and nerve tissue.

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Numerology

1. Chaldean Numerology

   The numerical value of amitotic in Chaldean Numerology is: 7

2. Pythagorean Numerology

   The numerical value of amitotic in Pythagorean Numerology is: 9

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=amitotic
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Amitotic
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Amitotic
4. ^ ChatGPT
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