What does akathisia mean?

Definitions for akathisia
akathisi·a

This dictionary definitions page includes all the possible meanings, example usage and translations of the word akathisia.


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Wiktionary

  1. akathisianoun

    a sensation of restlessness characterized by an inability to sit still or remain motionless, often as a side effect of psychiatric medications

  2. Etymology: from ancient Greek α (a), [without, not] + κάθισις (káthisis), [sitting]

Wikipedia

  1. Akathisia

    Akathisia is a movement disorder characterized by a subjective feeling of inner restlessness accompanied by mental distress and an inability to sit still. Usually, the legs are most prominently affected. Those affected may fidget, rock back and forth, or pace, while some may just have an uneasy feeling in their body. The most severe cases may result in aggression, violence, and/or suicidal thoughts. Akathisia is also associated with threatening behaviour and physical aggression that is greatest in patients with mild akathisia, and diminishing with increasing severity of akathisia.Antipsychotic medication, particularly the first generation antipsychotics, are a leading cause. Other agents commonly responsible for this side-effect may also include selective serotonin reuptake inhibitors, metoclopramide, and reserpine, though any medication listing agitation as a side effect may trigger it. It may also occur upon stopping antipsychotics. The underlying mechanism is believed to involve dopamine. Diagnosis is based on the symptoms. It differs from restless leg syndrome in that akathisia is not associated with sleeping. However, despite a lack of historical association between restless leg syndrome and akathisia, this does not guarantee that the two conditions do not share symptoms in individual cases. Treatment may include switching to an antipsychotic with a lower risk of the condition, if the akathisia was caused by an antipsychotic. The antidepressant mirtazapine has demonstrated benefit, as well as diphenhydramine, trazodone, benzatropine, cyproheptadine, and beta blockers, particularly propranolol. The term was first used by Czech neuropsychiatrist Ladislav Haškovec, who described the phenomenon in 1901 long before the discovery of antipsychotics, with drug-induced akathisia first being described in 1960. It is from Greek a-, meaning "not", and καθίζειν kathízein, meaning "to sit", or in other words an "inability to sit".

Wikidata

  1. Akathisia

    Akathisia, or acathisia, is a syndrome characterized by unpleasant sensations of inner restlessness that manifests itself with an inability to sit still or remain motionless. It can be a side effect of medications, or it can, to a lesser extent, be caused by Parkinson's disease and related syndromes, and likely other neurological diseases. However, this may be due more to the drugs used in treatment such as sinemet and less with the Parkinson's disease itself. Another major cause is withdrawal from almost any physical addiction, for example, in benzodiazepine withdrawal syndrome. It was discovered that akathisia involves increased levels of the neurotransmitter norepinephrine, which is associated with mechanisms that regulate aggression, alertness, and arousal. Though no further research has been done yet, it may also be involved with disrupted NMDA channels in the brain, which have both synergistic and regulatory effects on norepinephrine.

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Numerology

  1. Chaldean Numerology

    The numerical value of akathisia in Chaldean Numerology is: 1

  2. Pythagorean Numerology

    The numerical value of akathisia in Pythagorean Numerology is: 7

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"akathisia." Definitions.net. STANDS4 LLC, 2024. Web. 23 Apr. 2024. <https://www.definitions.net/definition/akathisia>.

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