Definitions for adenosylmethionine decarboxylase
adeno·syl·me·thio·n·ine de·car·boxy·lase

WikipediaRate this definition:0.0 / 0 votes

1. Adenosylmethionine decarboxylase

   The enzyme adenosylmethionine decarboxylase (EC 4.1.1.50) catalyzes the conversion of S-adenosyl methionine to S-adenosylmethioninamine. Polyamines such as spermidine and spermine are essential for cellular growth under most conditions, being implicated in many cellular processes including DNA, RNA and protein synthesis. S-adenosylmethionine decarboxylase (AdoMetDC) plays an essential regulatory role in the polyamine biosynthetic pathway by generating the n-propylamine residue required for the synthesis of spermidine and spermine from putrescein. Unlike many amino acid decarboxylases AdoMetDC uses a covalently bound pyruvate residue as a cofactor rather than the more common pyridoxal 5'-phosphate. These proteins can be divided into two main groups which show little sequence similarity either to each other, or to other pyruvoyl-dependent amino acid decarboxylases: class I enzymes found in bacteria and archaea, and class II enzymes found in eukaryotes. In both groups the active enzyme is generated by the post-translational autocatalytic cleavage of a precursor protein. This cleavage generates the pyruvate precursor from an internal serine residue and results in the formation of two non-identical subunits termed alpha and beta which form the active enzyme.

WikidataRate this definition:0.0 / 0 votes

1. Adenosylmethionine decarboxylase

   Adenosylmethionine decarboxylase is an enzyme that catalyzes the conversion of S-adenosyl methionine to S-adenosylmethioninamine. Polyamines such as spermidine and spermine are essential for cellular growth under most conditions, being implicated in a large number of cellular processes including DNA, RNA and protein synthesis. S-adenosylmethionine decarboxylase plays an essential regulatory role in the polyamine biosynthetic pathway by generating the n-propylamine residue required for the synthesis of spermidine and spermine from putrescein. Unlike many amino acid decarboxylases AdoMetDC uses a covalently bound pyruvate residue as a cofactor rather than the more common pyridoxal 5'-phosphate. These proteins can be divided into two main groups which show little sequence similarity either to each other, or to other pyruvoyl-dependent amino acid decarboxylases: class I enzymes found in bacteria and archaea, and class II enzymes found in eukaryotes. In both groups the active enzyme is generated by the post-translational autocatalytic cleavage of a precursor protein. This cleavage generates the pyruvate precursor from an internal serine residue and results in the formation of two non-identical subunits termed alpha and beta which form the active enzyme.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Adenosylmethionine Decarboxylase

   An enzyme that catalyzes the decarboxylation of S-adenosyl-L-methionine to yield 5'-deoxy-(5'-),3-aminopropyl-(1), methylsulfonium salt. It is one of the enzymes responsible for the synthesis of spermidine from putrescine. EC 4.1.1.50.

How to pronounce adenosylmethionine decarboxylase?

1. Alex

   US English

   David

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   Mark

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   Daniel

   British

   Libby

   British

   Mia

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   Karen

   Australian

   Hayley

   Australian

   Natasha

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   Indian

   Priya

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   Neerja

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   Zira

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   Oliver

   British

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   Fred

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   Tessa

   South African

How to say adenosylmethionine decarboxylase in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of adenosylmethionine decarboxylase in Chaldean Numerology is: 5

2. Pythagorean Numerology

   The numerical value of adenosylmethionine decarboxylase in Pythagorean Numerology is: 8

References

1. ^ Wikipedia
   https://en.wikipedia.org/wiki/Adenosylmethionine_Decarboxylase
2. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=adenosylmethionine decarboxylase