What does STATIN mean?
Definitions for STATIN
statin
This dictionary definitions page includes all the possible meanings, example usage and translations of the word STATIN.
Princeton's WordNet
lipid-lowering medicine, lipid-lowering medication, statin drug, statinnoun
a medicine that lowers blood cholesterol levels by inhibiting HMG-CoA reductase
Wiktionary
statinnoun
Any of a class of drugs (chiefly lactones or pyrroles) that lower the amount of cholesterol in the blood by inhibiting an enzyme involved in its biosynthesis.
Etymology: From the suffix -statin, from terms such as lovastatin and simvastatin.
Wikipedia
Statin
Statins, also known as HMG-CoA reductase inhibitors, are a class of lipid-lowering medications that reduce illness and mortality in those who are at high risk of cardiovascular disease. They are the most common cholesterol-lowering drugs.Low-density lipoprotein (LDL) carriers of cholesterol play a key role in the development of atherosclerosis and coronary heart disease via the mechanisms described by the lipid hypothesis. Statins are effective in lowering LDL cholesterol and so are widely used for primary prevention in people at high risk of cardiovascular disease, as well as in secondary prevention for those who have developed cardiovascular disease.Side effects of statins include muscle pain, increased risk of diabetes mellitus, and abnormal blood levels of liver enzymes. Additionally, they have rare but severe adverse effects, particularly muscle damage. They inhibit the enzyme HMG-CoA reductase which plays a central role in the production of cholesterol. High cholesterol levels have been associated with cardiovascular disease.There are various forms of statins, some of which include atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin, and simvastatin. Combination preparations of a statin and another agent, such as ezetimibe/simvastatin, are also available. The class is on the World Health Organization's List of Essential Medicines with simvastatin being the listed medicine. In 2005, sales were estimated at US$18.7 billion in the United States. The best-selling statin is atorvastatin, also known as Lipitor, which in 2003 became the best-selling pharmaceutical in history. The manufacturer Pfizer reported sales of US$12.4 billion in 2008. Due to patent expirations, several statins became available in 2016 as less expensive generics.
ChatGPT
statin
A statin is a type of drug used to lower cholesterol levels in the blood. This is accomplished by inhibiting the enzyme HMG-CoA reductase, which plays a crucial role in the production of cholesterol in the liver. Statins are commonly prescribed to individuals at risk of cardiovascular disease due to high cholesterol levels.
Wikidata
Statin
Statins are a class of drugs used to lower cholesterol levels by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the production of cholesterol in the liver. Increased cholesterol levels have been associated with cardiovascular diseases, and statins are therefore used in the prevention of these diseases. Research has found that statins are most effective for treating cardiovascular disease as a secondary prevention strategy, with questionable benefit in those with elevated cholesterol levels but without previous CVD. Statins have rare but severe adverse effects, particularly muscle damage, and some doctors believe they are overprescribed. The best-selling statin is atorvastatin, marketed as Lipitor and Torvast. By 2003, atorvastatin became the best-selling pharmaceutical in history, with Pfizer reporting sales of US$12.4 billion in 2008. As of 2010, a number of statins are on the market: atorvastatin, fluvastatin, lovastatin, pitavastatin, pravastatin, rosuvastatin and simvastatin. Several combination preparations of a statin and another agent, such as ezetimibe/simvastatin, are also available.
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Anagrams for STATIN »
taints
tanist
titans
Titans
Numerology
Chaldean Numerology
The numerical value of STATIN in Chaldean Numerology is: 9
Pythagorean Numerology
The numerical value of STATIN in Pythagorean Numerology is: 2
Examples of STATIN in a Sentence
The risk enhancers may increase a patient's short-term, 10-year risk, or in some cases, their lifetime risk of having a cardiovascular event, then those guidelines recommend that clinicians should err on the side of early treatment, something not considered in The Task Force The Task Force, but I do want to emphasize, even if clinicians were to take the more conservative The Task Force recommendations and follow them very, very aggressively, we definitely will see a population-level impact because of the statin therapy. The Task Force's really been studied for a very, very long time and now we know The Task Force works.
Overall, the serious risk for serious, adverse events is very low and so the risk benefit will usually be in favor of a statin for individuals at risk, statins can be very helpful for long-term risk reduction and with very minimal side effects and great benefits. It's one of those key medications that have changed the face of medicine.
I see heart patients that come in with terrible histories, multiple myocardial infarction, sometimes bypass surgery, many stents and they say, ‘Doctor, I’ve tried multiple statins, but whenever I take a statin, my muscles hurt, or they’re weak. I can’t walk upstairs. I just can’t tolerate these drugs,’ we do need alternatives for these patients.
As with any observational study, we cannot say for certain that the associations we describe between statin use and reduced severity of COVID-19 infection are definitely due to the statins themselves; however, we can now say with very strong evidence that they may play a role in substantially lowering a patient’s risk of death from COVID-19, we hope that our research findings are an incentive for patients to continue with their medication.
Would you really want to give them a statin when lifestyle could take care of the problem? we believe in careful, thoughtful use of statins.
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Translations for STATIN
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"STATIN." Definitions.net. STANDS4 LLC, 2024. Web. 18 Apr. 2024. <https://www.definitions.net/definition/STATIN>.
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