What does Ryanodine mean?
Definitions for Ryanodine
ryan·odine
This dictionary definitions page includes all the possible meanings, example usage and translations of the word Ryanodine.
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Wiktionary
ryanodinenoun
A poisonous alkaloid found in the South American plant Ryania speciosa, originally used as an insecticide.
Wikidata
Ryanodine
Ryanodine is a poisonous alkaloid found in the South American plant Ryania speciosa. It was originally used as an insecticide. The compound has extremely high affinity to the open-form ryanodine receptor, a group of calcium channels found in skeletal and heart muscle cells. It binds with such high affinity to the receptor that it was used as a label for the first purification of that class of ion channels and gave its name to it. At nanomolar concentrations, ryanodine locks the receptor in a half-open state, whereas it fully closes them at micromolar concentration. The effect of the nanomolar-level binding is that ryanodine causes release of calcium from calcium stores in the sarcoplasmic reticulum leading to massive muscular contractions. This is true for both mammals and insects.
U.S. National Library of Medicine
Ryanodine
A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
Numerology
Chaldean Numerology
The numerical value of Ryanodine in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of Ryanodine in Pythagorean Numerology is: 6
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"Ryanodine." Definitions.net. STANDS4 LLC, 2024. Web. 18 Apr. 2024. <https://www.definitions.net/definition/Ryanodine>.
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