Definitions for POEMS syndrome
po·em·s syn·drome

WikipediaRate this definition:0.0 / 0 votes

1. POEMS syndrome

   POEMS syndrome (also termed osteosclerotic myeloma, Crow–Fukase syndrome, Takatsuki disease, or PEP syndrome) is a rare paraneoplastic syndrome caused by a clone of aberrant plasma cells. The name POEMS is an acronym for some of the disease's major signs and symptoms (polyneuropathy, organomegaly, endocrinopathy, myeloma protein, and skin changes), as is PEP (polyneuropathy, endocrinopathy, plasma cell dyscrasia). The signs and symptoms of most neoplasms are due to their mass effects caused by the invasion and destruction of tissues by the neoplasms' cells. Signs and symptoms of a cancer causing a paraneoplastic syndrome result from the release of humoral factors such as hormones, cytokines, or immunoglobulins by the syndrome's neoplastic cells and/or the response of the immune system to the neoplasm. Many of the signs and symptoms in POEMS syndrome are due at least in part to the release of an aberrant immunoglobulin, i.e. a myeloma protein, as well as certain cytokines by the malignant plasma cells.POEMS syndrome typically begins in middle age – the average age at onset is 50 – and affects up to twice as many men as women.

WikidataRate this definition:0.0 / 0 votes

1. POEMS syndrome

   POEMS syndrome is a rare medical syndrome. It is defined as the combination of a plasma-cell proliferative disorder, polyneuropathy, and effects on many other organ systems. It begins in middle age – the average age at onset is 50 – and affects up to twice as many men as women. If untreated it is progressive and often fatal, with only 60% of sufferers remaining alive five years after onset. However, the symptoms can improve if the blood disorder is successfully treated. The name 'POEMS syndrome', now the most prevalent, was coined in 1980 by Bardwick et al. The name is an acronym deriving from some of the main features: Polyneuropathy, Organomegaly, Endocrinopathy or Edema, M-protein and Skin abnormalities. However, these features are neither an exhaustive list nor seen in all individuals with the condition.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. POEMS Syndrome

   A multisystemic disorder characterized by a sensorimotor polyneuropathy (POLYNEUROPATHIES), organomegaly, endocrinopathy, monoclonal gammopathy, and pigmentary skin changes. Other clinical features which may be present include EDEMA; CACHEXIA; microangiopathic glomerulopathy; pulmonary hypertension (HYPERTENSION, PULMONARY); cutaneous necrosis; THROMBOCYTOSIS; and POLYCYTHEMIA. This disorder is frequently associated with osteosclerotic myeloma. (From Adams et al., Principles of Neurology, 6th ed, p1335; Rev Med Interne 1997;18(7):553-62)

How to pronounce POEMS syndrome?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say POEMS syndrome in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of POEMS syndrome in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of POEMS syndrome in Pythagorean Numerology is: 1

References

1. ^ Wikipedia
   https://en.wikipedia.org/wiki/Poems_Syndrome
2. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=POEMS syndrome