Definitions for Coniine
ˈkoʊ niˌin, -ɪn, -nin; -nɪn; -nin, -nɪnconi·ine

WiktionaryRate this definition:0.0 / 0 votes

1. coniinenoun

   A poisonous alkaloid found in poison hemlock and the yellow pitcher plant; it is a neurotoxin which disrupts the peripheral nervous system.

WikipediaRate this definition:0.0 / 0 votes

1. Coniine

   Coniine is a poisonous chemical compound, an alkaloid present in and isolable from poison hemlock (Conium maculatum), where its presence has been a source of significant economic, medical, and historico-cultural interest; coniine is also produced by the yellow pitcher plant (Sarracenia flava), and fool's parsley (Aethusa cynapium). Its ingestion and extended exposure are toxic to humans and all classes of livestock; its mechanism of poisoning involves disruption of the central nervous system, with death caused by respiratory paralysis. The biosynthesis of coniine contains as its penultimate step the non-enzymatic cyclisation of 5-oxooctylamine to γ-coniceine, a Schiff base differing from coniine only by its carbon-nitrogen double bond in the ring. This pathway results in natural coniine that is a mixture—a racemate—composed of two enantiomers, the stereoisomers (S)-(+)-coniine and (R)-(−)-coniine, depending on the direction taken by the chain that branches from the ring. Both enantiomers are toxic, with the (R)-enantiomer being the more biologically active and toxic of the two in general. Coniine holds a place in organic chemistry history as being the first of the important class of alkaloids to be synthesized, by Albert Ladenburg in 1886, and it has been synthesized in the laboratory in a number of unique ways through to modern times. Hemlock poisoning has been a periodic human concern, a regular veterinary concern, and has had significant occurrences in human and cultural history. Notably, in 399 BC, Socrates was sentenced to death by drinking a coniine-containing mixture of poison hemlock.

Webster DictionaryRate this definition:0.0 / 0 votes

1. Coniinenoun

   see Conine

WikidataRate this definition:0.0 / 0 votes

1. Coniine

   Coniine is a poisonous alkaloid found in poison hemlock and the yellow pitcher plant, and contributes to hemlock's fetid smell. It is a neurotoxin which disrupts the peripheral nervous system. It is toxic to humans and all classes of livestock; less than 0.2g is fatal to humans, with death caused by respiratory paralysis. Socrates was put to death by means of this poison in 399 BC. Coniine has two stereoisomers:--coniine, and--coniine, both of which are present in hemlock. Coniine was first synthesized by Albert Ladenburg in 1886; it was the first of the alkaloids to be synthesized.

How to pronounce Coniine?

1. Alex

   US English

   David

   US English

   Mark

   US English

   Daniel

   British

   Libby

   British

   Mia

   British

   Karen

   Australian

   Hayley

   Australian

   Natasha

   Australian

   Veena

   Indian

   Priya

   Indian

   Neerja

   Indian

   Zira

   US English

   Oliver

   British

   Wendy

   British

   Fred

   US English

   Tessa

   South African

How to say Coniine in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of Coniine in Chaldean Numerology is: 9

2. Pythagorean Numerology

   The numerical value of Coniine in Pythagorean Numerology is: 6

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Coniine
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Coniine
3. ^ Webster Dictionary
   https://www.merriam-webster.com/dictionary/Coniine
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=Coniine