Definitions for Chronic Granulomatous Disease
chron·ic gran·u·lo·ma·tous disease

WiktionaryRate this definition:0.0 / 0 votes

1. chronic granulomatous diseasenoun

   Any of a group of hereditary defects in the ability of some phagocytes to kill certain bacteria; the resulting infection

WikipediaRate this definition:0.0 / 0 votes

1. Chronic granulomatous disease

   Chronic granulomatous disease (CGD), also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome, is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens. This leads to the formation of granulomas in many organs. CGD affects about 1 in 200,000 people in the United States, with about 20 new cases diagnosed each year.This condition was first discovered in 1950 in a series of 4 boys from Minnesota, and in 1957 it was named "a fatal granulomatosus of childhood" in a publication describing their disease. The underlying cellular mechanism that causes chronic granulomatous disease was discovered in 1967, and research since that time has further elucidated the molecular mechanisms underlying the disease. Bernard Babior made key contributions in linking the defect of superoxide production of white blood cells, to the cause of the disease. In 1986, the X-linked form of CGD was the first disease for which positional cloning was used to identify the underlying genetic mutation.

WikidataRate this definition:0.0 / 0 votes

1. Chronic granulomatous disease

   Chronic granulomatous disease is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds used to kill certain ingested pathogens. This leads to the formation of granulomata in many organs. CGD affects about 1 in 200,000 people in the United States, with about 20 new cases diagnosed each year. This condition was first discovered in 1950 in a series of 4 boys from Minnesota, and in 1957 was named "a fatal granulomatosus of childhood" in a publication describing their disease. The underlying cellular mechanism that causes chronic granulomatous disease was discovered in 1967, and research since that time has further elucidated the molecular mechanisms underlying the disease. In 1986, the x-linked form of CGD was the first disease for which positional cloning was used to identify the underlying genetic mutation.

How to pronounce Chronic Granulomatous Disease?

1. Alex

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   Mark

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   Daniel

   British

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How to say Chronic Granulomatous Disease in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of Chronic Granulomatous Disease in Chaldean Numerology is: 1

2. Pythagorean Numerology

   The numerical value of Chronic Granulomatous Disease in Pythagorean Numerology is: 3

References

1. ^ Wiktionary
   https://en.wiktionary.org/wiki/Chronic_Granulomatous_Disease
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Chronic_Granulomatous_Disease
3. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=Chronic Granulomatous Disease