Definitions for Cervical Intraepithelial Neoplasia
cer·vi·cal in·traep·ithe·lial neo·pla·si·a

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1. Cervical intraepithelial neoplasia

   Cervical intraepithelial neoplasia, also known as cervical dysplasia and cervical interstitial neoplasia, is the potentially premalignant transformation and abnormal growth of squamous cells on the surface of the cervix. CIN is not cancer, and is usually curable. Most cases of CIN remain stable, or are eliminated by the host's immune system without intervention. However a small percentage of cases progress to become cervical cancer, usually cervical squamous cell carcinoma, if left untreated. The major cause of CIN is chronic infection of the cervix with the sexually transmitted human papillomavirus, especially the high-risk HPV types 16 or 18. Over 100 types of HPV have been identified. About a dozen of these types appear to cause cervical dysplasia and may lead to the development of cervical cancer. Other types cause warts. The earliest microscopic change corresponding to CIN is dysplasia of the epithelial or surface lining of the cervix, which is essentially undetectable by the woman. Cellular changes associated with HPV infection, such as koilocytes, are also commonly seen in CIN. CIN is usually discovered by a screening test, the Papanicolaou or "Pap" smear. The purpose of this test is to detect potentially precancerous changes. Pap smear results may be reported using the Bethesda System. An abnormal Pap smear result may lead to a recommendation for colposcopy of the cervix, during which the cervix is examined under magnification. A biopsy is taken of any abnormal appearing areas. Cervical dysplasia can be diagnosed by biopsy.

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1. Cervical Intraepithelial Neoplasia

   A malignancy arising in uterine cervical epithelium and confined thereto, representing a continuum of histological changes ranging from well-differentiated CIN 1 (formerly, mild dysplasia) to severe dysplasia/carcinoma in situ, CIN 3. The lesion arises at the squamocolumnar cell junction at the transformation zone of the endocervical canal, with a variable tendency to develop invasive epidermoid carcinoma, a tendency that is enhanced by concomitant human papillomaviral infection. (Segen, Dictionary of Modern Medicine, 1992)

How to pronounce Cervical Intraepithelial Neoplasia?

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Numerology

1. Chaldean Numerology

   The numerical value of Cervical Intraepithelial Neoplasia in Chaldean Numerology is: 8

2. Pythagorean Numerology

   The numerical value of Cervical Intraepithelial Neoplasia in Pythagorean Numerology is: 9

References

1. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=Cervical Intraepithelial Neoplasia