the stage of meiosis or mitosis when chromosomes move toward opposite ends of the nuclear spindle
the stage of mitosis and meiosis during which the chromosomes separate; the chromatid moving to opposite poles of the cell
Anaphase, from the ancient Greek ἀνά and φάσις, is the stage of mitosis or meiosis when chromosomes are split and the sister chromatids move to opposite poles of the cell. Anaphase accounts for approximately 1% of the cell cycle's duration. It begins with the regulated triggering of the metaphase-to-anaphase transition. Metaphase ends with the destruction of B cyclin. B cyclin is marked with ubiquitin which flags it for destruction by proteasomes, which is required for the function of metaphase cyclin-dependent kinases. Anaphase starts when the anaphase promoting complex marks an inhibitory chaperone called securin with ubiquitin for destruction. Securin is a protein which inhibits a protease known as separase. Once destroyed, separase is unleashed and breaks down cohesin, a protein responsible for holding sister chromatids together. The centromeres are split, and the new daughter chromosomes are pulled toward the poles. They take on a V-shape as they are pulled back. While the chromosomes are drawn to each side of the cell, the non-kinetochore spindle fibers push against each other, in a ratcheting action, that stretches the cell into an oval. Once anaphase is complete, the cell moves into telophase.
U.S. National Library of Medicine
The phase of cell nucleus division following METAPHASE, in which the CHROMATIDS separate and migrate to opposite poles of the spindle.
Anaphase is the 3rd phase of mitosis which is a process that separates the duplicated genetic material carried in the nucleus of a parent cell into two daughter cellsSubmitted by rinat on April 10, 2018
The numerical value of Anaphase in Chaldean Numerology is: 2
The numerical value of Anaphase in Pythagorean Numerology is: 2
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