Definitions for ANTIGEN
ˈæn tɪ dʒən, -ˌdʒɛnanti·gen

Princeton's WordNetRate this definition:0.0 / 0 votes

1. antigennoun

   any substance (as a toxin or enzyme) that stimulates an immune response in the body (especially the production of antibodies)

WiktionaryRate this definition:0.0 / 0 votes

1. antigennoun

   A substance that induces an immune response, usually foreign.

2. Etymology: From antigène, from anti- + gène.

WikipediaRate this definition:0.0 / 0 votes

1. Antigen

   In immunology, an antigen (Ag) is a molecule or molecular structure or any foreign particulate matter or a pollen grain that can bind to a specific antibody or T-cell receptor. The presence of antigens in the body may trigger an immune response. The term antigen originally referred to a substance that is an antibody generator. Antigens can be proteins, peptides (amino acid chains), polysaccharides (chains of monosaccharides/simple sugars), lipids, or nucleic acids.Antigens are recognized by antigen receptors, including antibodies and T-cell receptors. Diverse antigen receptors are made by cells of the immune system so that each cell has a specificity for a single antigen. Upon exposure to an antigen, only the lymphocytes that recognize that antigen are activated and expanded, a process known as clonal selection. In most cases, an antibody can only react to and bind one specific antigen; in some instances, however, antibodies may cross-react and bind more than one antigen. The antigen may originate from within the body ("self-protein") or from the external environment ("non-self"). The immune system identifies and attacks "non-self" external antigens and usually does not react to self-protein due to negative selection of T cells in the thymus and B cells in the bone marrow.Vaccines are examples of antigens in an immunogenic form, which are intentionally administered to a recipient to induce the memory function of the adaptive immune system towards antigens of the pathogen invading that recipient. The vaccine for seasonal influenza is a common example.

ChatGPTRate this definition:0.0 / 0 votes

1. antigen

   An antigen is a substance that triggers an immune response in the body, particularly the production of antibodies, because it is recognized as a foreign substance or pathogen. These can include bacteria, viruses, fungi, parasites, or toxins. Antigens "present" themselves on the surfaces of cells, where they can be recognized by immune cells.

WikidataRate this definition:3.0 / 2 votes

1. Antigen

   In immunology, an antigen is the substance that binds specifically to the respective antibody. Each antibody from the diverse repertoire binds a specific antigenic structure by means of its variable region interaction, in analogy to the fit between a lock and a key. Paul Ehrlich has coined the term antibody in his Side-chain theory at the end of 19th century. The term antigen originally came from ANTIbody GENerator. The antigen may originate from within the body or from the external environment. "Self" antigens are usually well tolerated by the immune system, which has been educated to non-reactivity against the structures present inside the body under the physiological conditions. "Non-self" antigens can be identified as invaders from the outside world or modified/harmful substances present under the distressed conditions in the body and only these are supposed to be attacked by the immune system. In other words, the immune system will try to destroy or neutralize any antigen that has been recognized as a foreign substance and/or signal of harmed tissues. In agreement with Hippocratic Corpus and the phrase Primum non nocere it keeps the homeostasis of the organism.

Matched Categories

1. • Immunology
   • Substance

Anagrams for ANTIGEN »

1. gentian

2. anteing

How to pronounce ANTIGEN?

1. Alex

   US English

   David

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   Mark

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   Daniel

   British

   Libby

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   Mia

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   Australian

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How to say ANTIGEN in sign language?

Numerology

1. Chaldean Numerology

   The numerical value of ANTIGEN in Chaldean Numerology is: 6

2. Pythagorean Numerology

   The numerical value of ANTIGEN in Pythagorean Numerology is: 7

Examples of ANTIGEN in a Sentence

1. Michael Mina:

   Let's say it's a Monday or on Day Zero you get exposed. Day three, you might turn positive on a PCR later that night. Day three and a half or maybe early day four you might turn positive on an antigen test. And so, the whole idea of twice a week is to shave off a considerable part of people's infectious course, and so, if you're using it twice a week, even if you turn positive in the middle of your two tests, by the time you do test, especially because it's rapid, you'll be able to pull yourself out when you've only been spreading for one and a half or two days instead of five days and six days.

2. Roger Connor:

   The key project is the expansion of antigen bulk production which will come online in 2024. That will be what will create the next step change in our capacity.

3. The FDA:

   The guidance also provides recommendations to test developers, such as considering the potential for future viral genetic mutations when designing their test, and conducting their own routine monitoring to evaluate the potential impact of new and emerging viral genetic mutations, which may be the basis of viral variants, on the performance for molecular, antigen and serology SARS-CoV-2 tests.

4. San Diego-based ACON Laboratories Inc.:

   In contrast to other home tests which require testing twice within a two-to-three-day period (a process known as serial screening), the Flowflex COVID-19 Antigen Home Test has been authorized for use as a single test by individuals with or without symptoms. This will allow for the distribution of more affordable single-test packaging, resulting in greater access to home testing.

5. John Whyte:

   The antigen test commonly known as the rapid diagnostic test after which results are provided in minutes to an hour detects specific proteins on the viruss surface. Its usually highly accurate, but it ismore likely to miss an active infection compared to the molecular test, according to the U.S. Food and Drug Administration. Meanwhile, the molecular test, also known as the RT-PCR test, nucleic acid amplification test, or a NAAT or diagnostic test, detects the viruss genetic material and, depending ondemand in the lab, typically takes a day or up to a week for results. This test is highly accurate and usually does not need to be repeated. Those who havesymptoms but have a negative rapid antigen test may require a molecular test to see there isindeed an active infection, according tothe FDA. As it stands now, I think we trade off accuracy for speed, i think we will continue to improve these tests but thats also why being attuned to symptoms and practicing the public health strategies is the way to go for now. Ultimately, we need to do more surveillance testing to really see whats happening in the community. Dr. William Schaffner, a medical professor at Vanderbilt University and medical director of the National Foundation for Infectious Diseases, told Fox News that testing could play a role in certain situations, using a family with young children visiting grandparents as a key example. Testing could have a role in this, though not so much for grandma and grandpa who have [ likely ] been sheltered at home, he said. But William Schaffner, like John Whyte, expressed concerns over testing accuracy and providing a false sense of security to those who receive the test. I think you have to inquire on the front end how long it takes for the results to come back, it tells you what your status is on that day.

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=ANTIGEN
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Antigen
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Antigen
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=ANTIGEN