What does AGER mean?

Definitions for AGER
ager

This dictionary definitions page includes all the possible meanings, example usage and translations of the word AGER.


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Wiktionary

  1. agernoun

    That which ages something.

Wikipedia

  1. ager

    RAGE (receptor for advanced glycation endproducts), also called AGER, is a 35 kilodalton transmembrane receptor of the immunoglobulin super family which was first characterized in 1992 by Neeper et al. Its name comes from its ability to bind advanced glycation endproducts (AGE), which include chiefly glycoproteins, the glycans of which have been modified non-enzymatically through the Maillard reaction. In view of its inflammatory function in innate immunity and its ability to detect a class of ligands through a common structural motif, RAGE is often referred to as a pattern recognition receptor. RAGE also has at least one other agonistic ligand: high mobility group protein B1 (HMGB1). HMGB1 is an intracellular DNA-binding protein important in chromatin remodeling which can be released by necrotic cells passively, and by active secretion from macrophages, natural killer cells, and dendritic cells. The interaction between RAGE and its ligands is thought to result in pro-inflammatory gene activation. Due to an enhanced level of RAGE ligands in diabetes or other chronic disorders, this receptor is hypothesised to have a causative effect in a range of inflammatory diseases such as diabetic complications, Alzheimer's disease and even some tumors. Isoforms of the RAGE protein, which lack the transmembrane and the signaling domain (commonly referred to as soluble RAGE or sRAGE) are hypothesized to counteract the detrimental action of the full-length receptor and are hoped to provide a means to develop a cure against RAGE-associated diseases.

Wikidata

  1. Ager

    The Ager is a river in Upper Austria; it is the discharge of the Attersee by Kammer Schörfling and Seewalchen, and by Lambach it flows into the Traun. The Ager emerged towards the end of the Würm glaciation, when the mighty glaciers began to melt. Influx into the Ager: ⁕The Vöckla flows into the Ager by Vöcklabruck ⁕The Aurach River flows into the Ager by Wankham ⁕The Redlbach flows into the Ager shortly before Schwanenstadt Over the Attersee the Ager also receives water from the Mondsee, the Zeller See and the Fuschlsee, that are all connected by relatively short streams. In the postwar period, the Ager was strongly polluted by various nearby factories. Today this is less the case because several sewage treatment plants have been created.

Suggested Resources

  1. AGER

    What does AGER stand for? -- Explore the various meanings for the AGER acronym on the Abbreviations.com website.

Surnames Frequency by Census Records

  1. AGER

    According to the U.S. Census Bureau, Ager is ranked #18703 in terms of the most common surnames in America.

    The Ager surname appeared 1,469 times in the 2010 census and if you were to sample 100,000 people in the United States, approximately 1 would have the surname Ager.

    83.1% or 1,222 total occurrences were White.
    11.3% or 167 total occurrences were Black.
    2.5% or 38 total occurrences were of Hispanic origin.
    1.2% or 19 total occurrences were of two or more races.
    1.2% or 18 total occurrences were Asian.
    0.3% or 5 total occurrences were American Indian or Alaskan Native.

Anagrams for AGER »

  1. areg

  2. gear

  3. GRAE

  4. rage

  5. agre

  6. gare

How to pronounce AGER?

How to say AGER in sign language?

Numerology

  1. Chaldean Numerology

    The numerical value of AGER in Chaldean Numerology is: 2

  2. Pythagorean Numerology

    The numerical value of AGER in Pythagorean Numerology is: 4

Popularity rank by frequency of use

AGER#10000#48491#100000

Translations for AGER

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"AGER." Definitions.net. STANDS4 LLC, 2024. Web. 28 Mar. 2024. <https://www.definitions.net/definition/AGER>.

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