What does 4-hydroxycoumarins mean?

Definitions for 4-hydroxycoumarins

Here are all the possible meanings and translations of the word 4-hydroxycoumarins.


  1. 4-Hydroxycoumarins

    4-Hydroxycoumarins are a class of vitamin K antagonist anticoagulant drug molecules derived from coumarin by adding a hydroxy group at the 4 position to obtain "4-hydroxycoumarin", then adding a large aromatic substituent at the 3-position. The large 3-position substituent is required for anticoagulant activity. The primary mechanism of the 4-hydroxycoumarin drugs is the inhibition of vitamin K epoxide reductase. These compounds are not direct antagonists of vitamin K, but rather act to deplete reduced vitamin K in tissues. For this reason vitamin K antagonizes their effect, and this has led to the loose terminology of vitamin K antagonism.

U.S. National Library of Medicine

  1. 4-Hydroxycoumarins

    Substances found in many plants, containing the 4-hydroxycoumarin radical. They interfere with vitamin K and the blood clotting mechanism, are tightly protein-bound, inhibit mitochondrial and microsomal enzymes, and are used as oral anticoagulants.


  1. Chaldean Numerology

    The numerical value of 4-hydroxycoumarins in Chaldean Numerology is: 3

  2. Pythagorean Numerology

    The numerical value of 4-hydroxycoumarins in Pythagorean Numerology is: 7

Images & Illustrations of 4-hydroxycoumarins

  1. 4-hydroxycoumarins4-hydroxycoumarins4-hydroxycoumarins


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