Wolfram syndrome, also called DIDMOAD, is a rare genetic disorder, causing diabetes mellitus, optic atrophy, and deafness as well as various other possible disorders. It was first described in four siblings in 1938 by Dr. Don J. Wolfram, M.D. The disease affects the brain and central nervous system.
U.S. National Library of Medicine
A hereditary condition characterized by multiple symptoms including those of DIABETES INSIPIDUS; DIABETES MELLITUS; OPTIC ATROPHY; and DEAFNESS. This syndrome is also known as DIDMOAD (first letter of each word) and is usually associated with VASOPRESSIN deficiency. It is caused by mutations in gene WFS1 encoding wolframin, a 100-kDa transmembrane protein.
The numerical value of wolfram syndrome in Chaldean Numerology is: 8
The numerical value of wolfram syndrome in Pythagorean Numerology is: 3
Images & Illustrations of wolfram syndrome
Find a translation for the wolfram syndrome definition in other languages:
Select another language:
Discuss these wolfram syndrome definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"wolfram syndrome." Definitions.net. STANDS4 LLC, 2017. Web. 18 Oct. 2017. <http://www.definitions.net/definition/wolfram syndrome>.