Definitions for vipoma
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A VIPoma is a rare endocrine tumor, usually originating from non-β islet cell of the pancreas, that produce vasoactive intestinal peptide. It may be associated with multiple endocrine neoplasia type 1. The massive amounts of VIP in turn cause profound and chronic watery diarrhea and resultant dehydration, hypokalemia, achlorhydria, acidosis, vasodilation, hypercalcemia and hyperglycemia.
U.S. National Library of Medicine
A tumor that secretes VASOACTIVE INTESTINAL PEPTIDE, a neuropeptide that causes VASODILATION; relaxation of smooth muscles; watery DIARRHEA; HYPOKALEMIA; and HYPOCHLORHYDRIA. Vipomas, derived from the pancreatic ISLET CELLS, generally are malignant and can secrete other hormones. In most cases, Vipomas are located in the PANCREAS but can be found in extrapancreatic sites.
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