Any of a group polypeptides that polymerize to form filaments in the cytoskeleton
Vimentin is a type III intermediate filament protein that is expressed in mesenchymal cells. IF proteins are found in all metazoan cells as well as bacteria. IF, along with tubulin-based microtubules and actin-based microfilaments, comprise the cytoskeleton. All IF proteins are expressed in a highly developmentally-regulated fashion; vimentin is the major cytoskeletal component of mesenchymal cells. Because of this, vimentin is often used as a marker of mesenchymally-derived cells or cells undergoing an epithelial-to-mesenchymal transition during both normal development and metastatic progression.
U.S. National Library of Medicine
An intermediate filament protein found in most differentiating cells, in cells grown in tissue culture, and in certain fully differentiated cells. Its insolubility suggests that it serves a structural function in the cytoplasm. MW 52,000.
The numerical value of vimentin in Chaldean Numerology is: 4
The numerical value of vimentin in Pythagorean Numerology is: 7
Images & Illustrations of vimentin
Find a translation for the vimentin definition in other languages:
Select another language: