Definitions for vicissitudevɪˈsɪs ɪˌtud, -ˌtyud
Random House Webster's College Dictionary
vi•cis•si•tudevɪˈsɪs ɪˌtud, -ˌtyud(n.)
regular change or succession of one state or thing to another.
change or variation; mutation; mutability.
vicissitudes, successive or changing phases or conditions, as of life or fortune; ups and downs.
Origin of vicissitude:
1560–70; < L vicissitūdō=viciss(im) in turn +cessim giving way, adv. der. of cēdere to go, proceed
a variation in circumstances or fortune at different times in your life or in the development of something
"the project was subject to the usual vicissitudes of exploratory research"
mutability in life or nature (especially successive alternation from one condition to another)
Regular change or succession from one thing to another, or one part of a cycle to the next; alternation; mutual succession; interchange.
a change, especially in one's life or fortunes.
regular change or succession from one thing to another; alternation; mutual succession; interchange
irregular change; revolution; mutation