Definitions for valproic acid
This page provides all possible meanings and translations of the word valproic acid
valproic acid, Depokene(noun)
anticonvulsant (trade name Depokene) used to prevent some kinds of seizures
The aliphatic carboxylic acid 2-propylpentanoic acid that is used as an anticonvulsant in the treatment of epilepsy etc
Valproic acid, an acidic chemical compound, has found clinical use as an anticonvulsant and mood-stabilizing drug, primarily in the treatment of epilepsy, bipolar disorder, and, less commonly, major depression. It is also used to treat migraine headaches and schizophrenia. VPA is a liquid at room temperature, but it can be reacted with a base such as sodium hydroxide to form the salt sodium valproate, which is a solid. The acid, salt, or a mixture of the two are marketed under the various brand names Depakote, Depakote ER, Depakene, Depakene Crono, Depacon, Depakine, Valparin and Stavzor. Approved uses of the various formulations vary by country; e.g., valproate semisodium is used as a mood stabilizer and also in the US as an anticonvulsant. VPA is a histone deacetylase inhibitor and is under investigation for treatment of HIV and various cancers.
U.S. National Library of Medicine
A fatty acid with anticonvulsant properties used in the treatment of epilepsy. The mechanisms of its therapeutic actions are not well understood. It may act by increasing GAMMA-AMINOBUTYRIC ACID levels in the brain or by altering the properties of voltage dependent sodium channels.
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