Definitions for urocanate hydratase
This page provides all possible meanings and translations of the word urocanate hydratase
U.S. National Library of Medicine
An enzyme that catalyzes the conversion of 4,5-dihydro-4-oxo-5-imidazolepropanoate to urocanate and water. EC 18.104.22.168.
Urocanase is the enzyme that catalyzes the second step in the degradation of histidine, the hydration of urocanate into imidazolonepropionate. urocanate + H₂O 4,5-dihydro-4-oxo-5-imidazolepropanoate Inherited deficiency of urocanase leads to elevated levels of urocanic acid in the urine, a condition known as urocanic aciduria. Urocanase is found in some bacteria, in the liver of many vertebrates and has also been found in the plant Trifolium repens. Urocanase is a protein of about 60 Kd, it binds tightly to NAD⁺ and uses it as an electrophil cofactor. A conserved cysteine has been found to be important for the catalytic mechanism and could be involved in the binding of the NAD⁺.
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"urocanate hydratase." Definitions.net. STANDS4 LLC, 2016. Web. 10 Feb. 2016. <http://www.definitions.net/definition/urocanate hydratase>.