Definitions for urobilinogen
This page provides all possible meanings and translations of the word urobilinogen
a chromogen formed in the intestine from the breakdown of bilirubin; yields urobilins on oxidation; some is excreted in the feces and some is resorbed and excreted in bile or urine
A colourless product of bilirubin reduction, formed in the intestines by bacterial action.
Urobilinogen is a colourless product of bilirubin reduction. It is formed in the intestines by bacterial action. Some urobilinogen is reabsorbed, taken up into the circulation and excreted by the kidney. This constitutes the normal "enterohepatic urobilinogen cycle". Increased amounts of bilirubin are formed in hemolysis, which generates increased urobilinogen in the gut. In liver disease, the intrahepatic urobilinogen cycle is inhibited also increasing urobilinogen levels. Urobilinogen is converted to the yellow pigmented urobilin apparent in urine. The urobilinogen in the intestine is then oxidized to brown stercobilin, which gives the feces their characteristic color. In biliary obstruction, below-normal amounts of conjugated bilirubin reach the intestine for conversion to urobilinogen. With limited urobilinogen available for reabsorption and excretion, the amount of urobilin found in the urine is low. High amounts of the soluble conjugated bilirubin enter the circulation where they are excreted via the kidneys. These mechanisms are responsible for the dark urine and pale stools observed in biliary obstruction. Low urine urobilinogen may result from complete obstructive jaundice or treatment with broad-spectrum antibiotics, which destroy the intestinal bacterial flora.
U.S. National Library of Medicine
A colorless compound formed in the intestines by the reduction of bilirubin. Some is excreted in the feces where it is oxidized to urobilin. Some is reabsorbed and re-excreted in the bile as bilirubin. At times, it is re-excreted in the urine, where it may be later oxidized to urobilin.
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"urobilinogen." Definitions.net. STANDS4 LLC, 2014. Web. 19 Apr. 2014. <http://www.definitions.net/definition/urobilinogen>.