Definitions for uracil mustard

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Wiktionary

  1. uracil mustard(Noun)

    uramustine

U.S. National Library of Medicine

  1. Uracil Mustard

    Nitrogen mustard derivative of URACIL. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.

Freebase

  1. Uramustine

    Uramustine or uracil mustard is a chemotherapy drug which belongs to the class of alkylating agents. It is used in lymphatic malignancies such as non-Hodgkin's lymphoma. It works by damaging DNA, primarily in cancer cells that preferentially take up the uracil due to their need to make nucleic acids during their rapid cycles of cell division. The DNA damage leads to apoptosis of the affected cells. Bone marrow suppression and nausea are the main side effects. Chemically it is a derivative of nitrogen mustard and uracil.

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