What does upregulation mean?
Definitions for upregulation
up·reg·u·la·tion
This dictionary definitions page includes all the possible meanings, example usage and translations of the word upregulation.
Wiktionary
upregulationnoun
The process, in the regulation of gene expression, in which the number, or activity of receptors increases in order to increase sensitivity
Wikipedia
upregulation
In the biological context of organisms' production of gene products, downregulation is the process by which a cell decreases the quantity of a cellular component, such as RNA or protein, in response to an external stimulus. The complementary process that involves increases of such components is called upregulation. An example of downregulation is the cellular decrease in the expression of a specific receptor in response to its increased activation by a molecule, such as a hormone or neurotransmitter, which reduces the cell's sensitivity to the molecule. This is an example of a locally acting (negative feedback) mechanism. An example of upregulation is the response of liver cells exposed to such xenobiotic molecules as dioxin. In this situation, the cells increase their production of cytochrome P450 enzymes, which in turn increases degradation of these dioxin molecules. Downregulation or upregulation of an RNA or protein may also arise by an epigenetic alteration. Such an epigenetic alteration can cause expression of the RNA or protein to no longer respond to an external stimulus. This occurs, for instance, during drug addiction or progression to cancer.
Numerology
Chaldean Numerology
The numerical value of upregulation in Chaldean Numerology is: 6
Pythagorean Numerology
The numerical value of upregulation in Pythagorean Numerology is: 6
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"upregulation." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/upregulation>.
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