Definitions for uniparental disomy
This page provides all possible meanings and translations of the word uniparental disomy
Uniparental disomy occurs when a person receives two copies of a chromosome, or of part of a chromosome, from one parent and no copies from the other parent. UPD can be the result of heterodisomy, in which a pair of non-identical chromosomes are inherited from one parent or isodisomy, in which a single chromosome from one parent is duplicated. Because it may lead to the duplication of lethal recessive genes, isodisomy is potentially dangerous, while heterodisomy is essentially benign.
U.S. National Library of Medicine
The presence in a cell of two paired chromosomes from the same parent, with no chromosome of that pair from the other parent. This chromosome composition stems from non-disjunction (NONDISJUNCTION, GENETIC) events during MEIOSIS. The disomy may be composed of both homologous chromosomes from one parent (heterodisomy) or a duplicate of one chromosome (isodisomy).
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"uniparental disomy." Definitions.net. STANDS4 LLC, 2014. Web. 11 Mar. 2014. <http://www.definitions.net/definition/uniparental disomy>.