Definitions for ubiquitin-protein ligases

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U.S. National Library of Medicine

  1. Ubiquitin-Protein Ligases

    A diverse class of enzymes that interact with UBIQUITIN-CONJUGATING ENZYMES and ubiquitination-specific protein substrates. Each member of this enzyme group has its own distinct specificity for a substrate and ubiquitin-conjugating enzyme. Ubiquitin-protein ligases exist as both monomeric proteins multiprotein complexes.


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