Definitions for ubiquitin-protein ligase complexes
This page provides all possible meanings and translations of the word ubiquitin-protein ligase complexes
U.S. National Library of Medicine
Ubiquitin-Protein Ligase Complexes
Complexes of enzymes that catalyze the covalent attachment of UBIQUITIN to other proteins by forming a peptide bond between the C-terminal GLYCINE of UBIQUITIN and the alpha-amino groups of LYSINE residues in the protein. The complexes play an important role in mediating the selective-degradation of short-lived and abnormal proteins. The complex of enzymes can be broken down into three components that involve activation of ubiquitin (UBIQUITIN-ACTIVATING ENZYMES), conjugation of ubiquitin to the ligase complex (UBIQUITIN-CONJUGATING ENZYMES), and ligation of ubiquitin to the substrate protein (UBIQUITIN-PROTEIN LIGASES).
Find a translation for the ubiquitin-protein ligase complexes definition in other languages:
Select another language:
Discuss these ubiquitin-protein ligase complexes definitions with the community:
Word of the Day
Would you like us to send you a FREE new word definition delivered to your inbox daily?
Use the citation below to add this definition to your bibliography:
"ubiquitin-protein ligase complexes." Definitions.net. STANDS4 LLC, 2015. Web. 29 Jul 2015. <http://www.definitions.net/definition/ubiquitin-protein ligase complexes>.