What does translatome mean?

Definitions for translatome
trans·latome

This dictionary definitions page includes all the possible meanings, example usage and translations of the word translatome.


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Wiktionary

  1. translatomenoun

    The totality of proteins formed by translation of mRNA

Wikipedia

  1. translatome

    Translatomics is the study of all open reading frames (ORFs) that are being actively translated in a cell or organism. This collection of ORFs is called the translatome. Characterizing a cell's translatome can give insight into the array of biological pathways that are active in the cell. According to the central dogma of molecular biology, the DNA in a cell is transcribed to produce RNA, which is then translated to produce a protein. Thousands of proteins are encoded in an organism's genome, and the proteins present in a cell cooperatively carry out many functions to support the life of the cell. Under various conditions, such as during stress or specific timepoints in development, the cell may require different biological pathways to be active, and therefore require a different collection of proteins. Depending on intrinsic and environmental conditions, the collection of proteins being made at one time varies. Translatomic techniques can be used to take a "snapshot" of this collection of actively translating ORFs, which can give information about which biological pathways the cell is activating under the present conditions.Usually, the ribosome profiling technique is used to acquire the translatome information. Other methods are polysome profiling, full-length translating mRNA profiling (RNC-seq), and translating ribosome affinity purification (TRAP-seq). Unlike the transcriptome, the translatome is a more accurate approximation for estimating the expression level of some genes, since the correlation between the proteome and translatome is higher than the correlation between the transcriptome and proteome.

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Numerology

  1. Chaldean Numerology

    The numerical value of translatome in Chaldean Numerology is: 3

  2. Pythagorean Numerology

    The numerical value of translatome in Pythagorean Numerology is: 3

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"translatome." Definitions.net. STANDS4 LLC, 2024. Web. 18 Mar. 2024. <https://www.definitions.net/definition/translatome>.

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