Definitions for tramadol
This page provides all possible meanings and translations of the word tramadol
A synthetic analgesic opiate used for the relief of pain.
Tramadol hydrochloride is a centrally acting synthetic analgesic used to treat moderate to moderately severe pain. The drug has a wide range of applications, including treatment of rheumatoid arthritis, restless legs syndrome, motor neurone disease and fibromyalgia. It was launched and marketed as Tramal by the German pharmaceutical company Grünenthal GmbH in 1977. Tramadol is a weak μ-opioid receptor agonist and is a reuptake inhibitor of serotonin and of norepinephrine. Tramadol is metabolized to O-desmethyltramadol, a significantly more potent μ-opioid agonist. Tramadol and its major metabolite are distinguished from other more potent opioid agonists by relative selectivity for μ-opioid receptors.
U.S. National Library of Medicine
A narcotic analgesic proposed for severe pain. It may be habituating.
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