| Definition of 'tnf-related apoptosis-inducing ligand' |
U.S. National Library of Medicine |
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1. tnf-related apoptosis-inducing ligand
A transmembrane-protein belonging to the TNF family of intercellular signaling proteins. It is a widely expressed ligand that activates APOPTOSIS by binding to TNF-RELATED APOPTOSIS-INDUCING LIGAND RECEPTORS. The membrane-bound form of the protein can be cleaved by specific CYSTEINE ENDOPEPTIDASES to form a soluble ligand form.
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Definitions of tnf-related apoptosis-inducing ligand
