Definitions for tissue plasminogen activator
tis·sue plas·mino·gen ac·ti·va·tor

Princeton's WordNetRate this definition:0.0 / 0 votes

1. tissue plasminogen activator, Activasenoun

   a thrombolytic agent (trade name Activase) that causes fibrinolysis at the site of a blood clot; used in treating acute myocardial infarction

WikipediaRate this definition:0.0 / 0 votes

1. Tissue plasminogen activator

   Tissue plasminogen activator (abbreviated tPA or PLAT) is a protein involved in the breakdown of blood clots. It is a serine protease (EC 3.4.21.68) found on endothelial cells, the cells that line the blood vessels. As an enzyme, it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown. Human tPA has a molecular weight of ~70 kDa in the single-chain form.tPA can be manufactured using recombinant biotechnology techniques; tPA produced by such means are referred to as recombinant tissue plasminogen activator (rtPA). Specific rtPAs include alteplase, reteplase, and tenecteplase. They are used in clinical medicine to treat embolic or thrombotic stroke. The use of this protein is contraindicated in hemorrhagic stroke and head trauma. The antidote for tPA in case of toxicity is aminocaproic acid.

ChatGPTRate this definition:0.0 / 0 votes

1. tissue plasminogen activator

   Tissue plasminogen activator (tPA) is a serine protease enzyme found in the body that plays a significant role in the breakdown of blood clots. This enzyme works by converting plasminogen, an inactive enzyme in the blood, into plasmin, which is an active enzyme that breaks down clots. It's most commonly used in medicine to treat conditions related to clots, such as strokes or heart attacks.

WikidataRate this definition:0.0 / 0 votes

1. Tissue plasminogen activator

   Tissue plasminogen activator is a protein involved in the breakdown of blood clots. It is a serine protease found on endothelial cells, the cells that line the blood vessels. As an enzyme, it catalyzes the conversion of plasminogen to plasmin, the major enzyme responsible for clot breakdown. Because it works on the clotting system, tPA is used in clinical medicine to treat embolic or thrombotic stroke. Use is contraindicated in hemorrhagic stroke and head trauma. tPA may be manufactured using recombinant biotechnology techniques. tPA created this way may be referred to as recombinant tissue plasminogen activator.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Tissue Plasminogen Activator

   A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.

Matched Categories

1. • Thrombolytic Agent

How to pronounce tissue plasminogen activator?

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Numerology

1. Chaldean Numerology

   The numerical value of tissue plasminogen activator in Chaldean Numerology is: 6

2. Pythagorean Numerology

   The numerical value of tissue plasminogen activator in Pythagorean Numerology is: 3

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=tissue plasminogen activator
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Tissue_Plasminogen_Activator
3. ^ ChatGPT
   https://chat.openai.com
4. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=tissue plasminogen activator