| Definition of 'tissue plasminogen activator' |
Princeton's WordNet |
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1. (noun) tissue plasminogen activator, Activase
a thrombolytic agent (trade name Activase) that causes fibrinolysis at the site of a blood clot; used in treating acute myocardial infarction
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| Definition of 'tissue plasminogen activator' |
U.S. National Library of Medicine |
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1. tissue plasminogen activator
A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.
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