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 Definitions of tetrahydrofolate dehydrogenase  

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Definition of 'tetrahydrofolate dehydrogenase' U.S. National Library of Medicine 

1.  tetrahydrofolate dehydrogenase
An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. (Dorland, 27th ed) EC 1.5.1.3.



'tetrahydrofolate dehydrogenase' - Nearby Entries  

tetradecanoylphorbol acetate  tetraethylammonium  tetragastrin  tetrahydrofolate dehydrogenase  tetrahydrofolates  tetrahydroisoquinolines  tetrahydronaphthalenes  



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