Definitions for tacrolimus
An immunosuppressive drug used mainly after organ transplantation.
Origin: From tsukuba macrolide immunosuppressant (after Streptomyces tsukubaensis).
U.S. National Library of Medicine
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.