Definitions for subacute sclerosing panencephalitissklɪˈroʊ sɪŋ ˈpæn ɛnˌsɛf əˈlaɪ tɪs, ˌpæn-
This page provides all possible meanings and translations of the word subacute sclerosing panencephalitis
subacute sclerosing panencephalitis, SSPE, inclusion body encephalitis, subacute inclusion body encephalitis, sclerosing leukoencephalitis, subacute sclerosing leukoencephalitis, Bosin's disease, Dawson's encephalitis, Van Bogaert encephalitis(noun)
a rare chronic progressive encephalitis caused by the measles virus and occurring primarily in children and young adults; death usually occurs within three years; characterized by primary measles infection before the age of two years
Subacute sclerosing panencephalitis
Subacute sclerosing panencephalitis is a rare chronic, progressive encephalitis that affects primarily children and young adults, caused by a persistent infection measles virus. No cure for SSPE exists, but the condition can be managed by medication if treatment is started at an early stage. Much of the work on SSPE has been performed by the National Institute of Neurological Disorders and Stroke. SSPE is also known as Dawson Disease, Dawson encephalitis and measles encephalitis. It should not be confused with acute disseminated encephalomyelitis which has a similar etiology but very different timing and course.
U.S. National Library of Medicine
Subacute Sclerosing Panencephalitis
A rare, slowly progressive encephalitis caused by chronic infection with the MEASLES VIRUS. The condition occurs primarily in children and young adults, approximately 2-8 years after the initial infection. A gradual decline in intellectual abilities and behavioral alterations are followed by progressive MYOCLONUS; MUSCLE SPASTICITY; SEIZURES; DEMENTIA; autonomic dysfunction; and ATAXIA. DEATH usually occurs 1-3 years after disease onset. Pathologic features include perivascular cuffing, eosinophilic cytoplasmic inclusions, neurophagia, and fibrous gliosis. It is caused by the SSPE virus, which is a defective variant of MEASLES VIRUS. (From Adams et al., Principles of Neurology, 6th ed, pp767-8)
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