What does sortase mean?
Definitions for sortase
sor·tase
This dictionary definitions page includes all the possible meanings, example usage and translations of the word sortase.
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Wiktionary
sortasenoun
Any of a group of prokaryotic enzymes that form pili through cleavage and isopeptide bonding of precursors.
Wikidata
Sortase
Sortase refers to a group of prokaryotic enzymes that modify surface proteins by recognizing and cleaving a carboxyl-terminal sorting signal. For most substrates of sortase enzymes, the recognition signal consists of the motif LPXTG, then a highly hydrophobic transmembrane sequence, then a cluster of basic residues such as arginine. Cleavage occurs between the Thr and Gly, with transient attachment through the Thr residue to the active site Cys residue, followed by transpeptidation that attaches the protein covalently to the cell wall. Sortases occur in almost all Gram-positive bacteria and the occasional Gram-negative or Archaea, where cell wall LPXTG-mediated decoration has not been reported. Although sortase A, the "housekeeping" sortase, typically acts on many targets per genome, other forms of sortase occur that recognize variant forms of the cleavage motif, or that catalyze the assembly of pilins into pili.
Numerology
Chaldean Numerology
The numerical value of sortase in Chaldean Numerology is: 7
Pythagorean Numerology
The numerical value of sortase in Pythagorean Numerology is: 7
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"sortase." Definitions.net. STANDS4 LLC, 2024. Web. 19 Apr. 2024. <https://www.definitions.net/definition/sortase>.
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