What does sirolimus mean?
Definitions for sirolimus
sirolimus
This dictionary definitions page includes all the possible meanings, example usage and translations of the word sirolimus.
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Wiktionary
sirolimusnoun
The drug rapamycin.
Wikidata
Sirolimus
Sirolimus, also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants. It prevents activation of T cells and B cells by inhibiting their response to interleukin-2. Sirolimus is also used as a coronary stent coating. A macrolide, sirolimus was discovered by Brazilian researchers as a product of the bacterium Streptomyces hygroscopicus in a soil sample from Easter Island — an island also known as Rapa Nui. It was approved by the FDA in September 1999 and is marketed under the trade name Rapamune by Pfizer. Sirolimus was originally developed as an antifungal agent. However, this use was abandoned when it was discovered to have potent immunosuppressive and antiproliferative properties. It has since been shown to prolong the life of mice and might also be useful in the treatment of certain cancers.
U.S. National Library of Medicine
Sirolimus
A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
Numerology
Chaldean Numerology
The numerical value of sirolimus in Chaldean Numerology is: 3
Pythagorean Numerology
The numerical value of sirolimus in Pythagorean Numerology is: 9
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Translations for sirolimus
From our Multilingual Translation Dictionary
- सिरोलिमसHindi
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"sirolimus." Definitions.net. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.definitions.net/definition/sirolimus>.
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