Definitions for simvastatin
This page provides all possible meanings and translations of the word simvastatin
an oral lipid-lowering medicine (trade name Zocor) administered to reduce blood cholesterol levels; recommended after heart attacks
A hypolipidemic drug used to control hypercholesterolemia and to prevent cardiovascular disease.
Simvastatin is a hypolipidemic drug used with exercise, diet, and weight-loss to control elevated cholesterol, or hypercholesterolemia. It is a member of the statin class of pharmaceuticals. Simvastatin is a synthetic derivative of a fermentation product of Aspergillus terreus. The drug is marketed generically following patent expiry, and under the trade name Zocor.
U.S. National Library of Medicine
A derivative of LOVASTATIN and potent competitive inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A reductase (HYDROXYMETHYLGLUTARYL COA REDUCTASES), which is the rate-limiting enzyme in cholesterol biosynthesis. It may also interfere with steroid hormone production. Due to the induction of hepatic LDL RECEPTORS, it increases breakdown of LDL CHOLESTEROL.
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