Definitions for sickle cell
sickle cell

Princeton's WordNetRate this definition:0.0 / 0 votes

1. sickle cellnoun

   an abnormal red blood cell that has a crescent shape and an abnormal form of hemoglobin

WikipediaRate this definition:0.0 / 0 votes

1. sickle cell

   Sickle cell disease (SCD) is a group of blood disorders typically inherited. The most common type is known as sickle cell anaemia. It results in an abnormality in the oxygen-carrying protein haemoglobin found in red blood cells. This leads to a rigid, sickle-like shape under certain circumstances. Problems in sickle cell disease typically begin around 5 to 6 months of age. A number of health problems may develop, such as attacks of pain (known as a sickle cell crisis), anemia, swelling in the hands and feet, bacterial infections and stroke. Long-term pain may develop as people get older. The average life expectancy in the developed world is 40 to 60 years.Sickle cell disease occurs when a person inherits two abnormal copies of the β-globin gene (HBB) that makes haemoglobin, one from each parent. This gene occurs in chromosome 11. Several subtypes exist, depending on the exact mutation in each haemoglobin gene. An attack can be set off by temperature changes, stress, dehydration, and high altitude. A person with a single abnormal copy does not usually have symptoms and is said to have sickle cell trait. Such people are also referred to as carriers. Diagnosis is by a blood test, and some countries test all babies at birth for the disease. Diagnosis is also possible during pregnancy.The care of people with sickle cell disease may include infection prevention with vaccination and antibiotics, high fluid intake, folic acid supplementation, and pain medication. Other measures may include blood transfusion and the medication hydroxycarbamide (hydroxyurea). A small percentage of people can be cured by a transplant of bone marrow cells.As of 2015, about 4.4 million people have sickle cell disease, while an additional 43 million have sickle cell trait. About 80% of sickle cell disease cases are believed to occur in Sub-Saharan Africa. It also occurs to a lesser degree in parts of India, Southern Europe, West Asia, North Africa and among people of African origin (sub-Saharan) living in other parts of the world. In 2015, it resulted in about 114,800 deaths. The condition was first described in the medical literature by American physician James B. Herrick in 1910. In 1949, its genetic transmission was determined by E. A. Beet and J. V. Neel. In 1954, the protective effect against malaria of sickle cell trait was described.

ChatGPTRate this definition:0.0 / 0 votes

1. sickle cell

   Sickle cell is a genetic blood disorder characterized by red blood cells that assume an abnormal, rigid, sickle (crescent) shape. These irregularly shaped cells can get stuck in small blood vessels, which can slow or block blood flow and oxygen to parts of the body, causing various complications. This condition is inherited when a child receives two sickle cell genes, one from each parent. Symptoms typically include anemia, recurring pain, frequent infections, delayed growth, and vision problems.

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1. • Red Blood Cell

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Numerology

1. Chaldean Numerology

   The numerical value of sickle cell in Chaldean Numerology is: 4

2. Pythagorean Numerology

   The numerical value of sickle cell in Pythagorean Numerology is: 1

References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=sickle cell
2. ^ Wikipedia
   https://en.wikipedia.org/wiki/Sickle_Cell
3. ^ ChatGPT
   https://chat.openai.com