Princeton's WordNet

1. Francis of Assisi, Saint Francis of Assisi, St. Francis of Assisi, Saint Francis, St. Francis, Giovanni di Bernardone(noun)

   (Roman Catholic Church) an Italian and the Roman Catholic monk who founded the Franciscan order of friars (1181-1226)

2. Saint Francis, Saint Francis River, St. Francis, St. Francis River(noun)

   a tributary of the Mississippi River that rises in Missouri and flows southeastward through Arkansas