Definitions for sain
To make the sign of the cross on or over something or someone.
To make the sign of the cross.
To bless, to keep from evil influence.
1983, The child was sained then. Fir candles were lighted and whirled round the bed in which mother and infant lay. u2014 Robert Nye, The Facts of Life
Origin: segnian, from signo.
to sanctify; to bless so as to protect from evil influence