Definitions for s-phase kinase-associated proteins

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U.S. National Library of Medicine

  1. S-Phase Kinase-Associated Proteins

    A family of structurally-related proteins that were originally identified by their ability to complex with cyclin proteins (CYCLINS). They share a common domain that binds specifically to F-BOX MOTIFS. They take part in SKP CULLIN F-BOX PROTEIN LIGASES, where they can bind to a variety of F-BOX PROTEINS.

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