What does rosiglitazone mean?
Definitions for rosiglitazone
rosigli·ta·zone
This dictionary definitions page includes all the possible meanings, example usage and translations of the word rosiglitazone.
Wiktionary
rosiglitazonenoun
A thiazolidinedione drug, used to treat diabetes (marketed as Avandia)
Wikidata
Rosiglitazone
Rosiglitazone is an antidiabetic drug in the thiazolidinedione class of drugs. It works as an insulin sensitizer, by binding to the PPAR receptors in fat cells and making the cells more responsive to insulin. It is marketed by the pharmaceutical company GlaxoSmithKline as a stand-alone drug or in combination with metformin or with glimepiride. First released in 1999, annual sales peaked at approximately $2.5bn in 2006, but declined after the drug was found to increase risk of heart attacks. The drug's patent expired in 2012. Concerns about rosiglitazone's adverse effects has reduced its use despite the benefits it offers in treating diabetes. Adverse effects caused by rosiglitazone are currently the subject of over 13,000 lawsuits against GSK. As of July 2010, GSK has agreed to settlements on more than 11,500 of these suits. The drug is controversial and is estimated to have caused 83,000 heart attacks in the United States alone. Some reviewers have recommended rosiglitazone be taken off the market, but a Food and Drug Administration panel disagreed, and it remains available in the U.S., subject to significant restrictions. From November 18, 2011, the federal government will not allow Avandia to be sold without a prescription from certified doctors. Patients will be required to be informed of the risks associated with its use, and the drug will be required to be purchased by mail order through specified pharmacies.
Numerology
Chaldean Numerology
The numerical value of rosiglitazone in Chaldean Numerology is: 4
Pythagorean Numerology
The numerical value of rosiglitazone in Pythagorean Numerology is: 8
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"rosiglitazone." Definitions.net. STANDS4 LLC, 2024. Web. 17 Apr. 2024. <https://www.definitions.net/definition/rosiglitazone>.
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