Definitions of rna-binding protein fus

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Definition of 'rna-binding protein fus'

U.S. National Library of Medicine

1. rna-binding protein fus
A multifunctional heterogeneous-nuclear ribonucleoprotein that may play a role in homologous DNA pairing and recombination. The N-terminal portion of protein is a potent transcriptional activator, while the C terminus is required for RNA binding. The name FUS refers to the fact that genetic recombination events result in fusion oncogene proteins (ONCOGENE PROTEINS, FUSION) that contain the N-terminal region of this protein. These fusion proteins have been found in myxoid liposarcoma (LIPOSARCOMA, MYXOID) and acute myeloid leukemia.

'rna-binding protein fus' - Nearby Entries
rna, untranslated rna, viral rna-binding protein ews rna-binding protein fus rna-binding proteins rna-directed dna polymerase rna-induced silencing complex

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