| Definition of 'ribosome inactivating proteins' |
U.S. National Library of Medicine |
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1. ribosome inactivating proteins
N-Glycosidases that remove adenines from RIBOSOMAL RNA, depurinating the conserved alpha-sarcin loop of 28S RIBOSOMAL RNA. They often consist of a toxic A subunit and a binding lectin B subunit. They may be considered as PROTEIN SYNTHESIS INHIBITORS. They are found in many PLANTS and have cytotoxic and antiviral activity.
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Definitions of ribosome inactivating proteins
