Definitions for reserpine
rəˈsɜr pɪn, -pinre·ser·pine

Princeton's WordNetRate this definition:0.0 / 0 votes

1. reserpine, Raudixin, Rau-Sed, Sandril, Serpasilnoun

   antihypertensive consisting of an alkaloid extracted from the plant Rauwolfia serpentina (trade names Raudixin or Rau-Sed or Sandril or Serpasil)

WiktionaryRate this definition:0.0 / 0 votes

1. reserpinenoun

   An alkaloid, isolated from the snakeroot plant, that is used as an antipsychotic and antihypertensive drug

WikipediaRate this definition:0.0 / 0 votes

1. Reserpine

   Reserpine is a drug that is used for the treatment of high blood pressure, usually in combination with a thiazide diuretic or vasodilator. Large clinical trials have shown that combined treatment with reserpine plus a thiazide diuretic reduces mortality of people with hypertension. Although the use of reserpine as a solo drug has declined since it was first approved by the FDA in 1955, the combined use of reserpine and a thiazide diuretic or vasodilator is still recommended in patients who do not achieve adequate lowering of blood pressure with first-line drug treatment alone. The reserpine-hydrochlorothiazide combo pill was the 17th most commonly prescribed of the 43 combination antihypertensive pills available In 2012.The antihypertensive actions of reserpine are largely due to its antinoradrenergic effects, which are a result of its ability to deplete catecholamines (among other monoamine neurotransmitters) from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral vascular resistance.At doses of 0.05 to 0.2 mg per day, reserpine is well tolerated; the most common adverse effect being nasal stuffiness. Reserpine has also been used for relief of psychotic symptoms. A review found that in persons with schizophrenia, reserpine and chlorpromazine had similar rates of adverse effects, but that reserpine was less effective than chlorpromazine for improving a person's global state.

ChatGPTRate this definition:0.0 / 0 votes

1. reserpine

   Reserpine is a naturally occurring medication derived from the plant Rauwolfia serpentina, also known as Indian Snakeroot. It is traditionally used in Indian and Chinese medicine. In modern medicine, it was used primarily as an antipsychotic and antihypertensive drug to reduce high blood pressure and to control symptoms of psychosis. However, due to significant side effects such as depression and a high risk of suicide, it is rarely used nowadays.

WikidataRate this definition:3.0 / 1 vote

1. Reserpine

   Reserpine is an indole alkaloid antipsychotic and antihypertensive drug that has been used for the control of high blood pressure and for the relief of psychotic symptoms, although because of the development of better drugs for these purposes and because of its numerous side-effects, it is rarely used today. The antihypertensive actions of reserpine are a result of its ability to deplete catecholamines from peripheral sympathetic nerve endings. These substances are normally involved in controlling heart rate, force of cardiac contraction and peripheral resistance. Reserpine mediated depletion of monoamine neurotransmitters in the synapses is often cited as evidence to the theory that depletion of the neurotransmitters causes subsequent depression in humans. However, this claim is not without controversy. The reserpine-induced depression is considered by some researchers to be a myth, while others claim that teas made out of the plant roots containing reserpine have a calming, sedative action that can actually be considered antidepressant. Notably, reserpine was the first compound shown to be an effective antidepressant in a randomized placebo-controlled trial.

U.S. National Library of MedicineRate this definition:0.0 / 0 votes

1. Reserpine

   An alkaloid found in the roots of Rauwolfia serpentina and R. vomitoria. Reserpine inhibits the uptake of norepinephrine into storage vesicles resulting in depletion of catecholamines and serotonin from central and peripheral axon terminals. It has been used as an antihypertensive and an antipsychotic as well as a research tool, but its adverse effects limit its clinical use.

Matched Categories

1. • Antihypertensive

How to pronounce reserpine?

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Numerology

1. Chaldean Numerology

   The numerical value of reserpine in Chaldean Numerology is: 9

2. Pythagorean Numerology

   The numerical value of reserpine in Pythagorean Numerology is: 1

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References

1. ^ Princeton's WordNet
   http://wordnetweb.princeton.edu/perl/webwn?s=reserpine
2. ^ Wiktionary
   https://en.wiktionary.org/wiki/Reserpine
3. ^ Wikipedia
   https://en.wikipedia.org/wiki/Reserpine
4. ^ ChatGPT
   https://chat.openai.com
5. ^ Wikidata
   https://www.wikidata.org/w/index.php?search=reserpine