Definitions of receptors, tumor necrosis factor, type i
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Definition of 'receptors, tumor necrosis factor, type i'
U.S. National Library of Medicine
1. receptors, tumor necrosis factor, type i A tumor necrosis factor receptor subtype that has specificity for TUMOR NECROSIS FACTOR ALPHA and LYMPHOTOXIN ALPHA. It is constitutively expressed in most tissues and is a key mediator of tumor necrosis factor signaling in the vast majority of cells. The activated receptor signals via a conserved death domain that associates with specific TNF RECEPTOR-ASSOCIATED FACTORS in the CYTOPLASM.
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Definitions of receptors, tumor necrosis factor, type i
