| Definition of 'receptor-interacting protein serine-threonine kinases' |
U.S. National Library of Medicine |
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1. receptor-interacting protein serine-threonine kinases
A family of serine-threonine kinases that plays a role in intracellular signal transduction by interacting with a variety of signaling adaptor proteins such as CRADD SIGNALING ADAPTOR PROTEIN; TNF RECEPTOR-ASSOCIATED FACTOR 2; and TNF RECEPTOR-ASSOCIATED DEATH DOMAIN PROTEIN. Although they were initially described as death domain-binding adaptor proteins, members of this family may contain other protein-binding domains such as those involving caspase activation and recruitment.
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Definitions of receptor-interacting protein serine-threonine kinases
