| Definition of 'receptor activator of nuclear factor-kappa b' |
U.S. National Library of Medicine |
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1. receptor activator of nuclear factor-kappa b
A tumor necrosis factor receptor family member that is specific for RANK LIGAND and plays a role in bone homeostasis by regulating osteoclastogenesis. It also expressed on DENDRITIC CELLS where is plays a role in regulating dendritic cell survival. Signaling by the activated receptor occurs through its association with TNF RECEPTOR-ASSOCIATED FACTORS.
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