A drug used in the treatment of osteoporosis
Raloxifene is an oral selective estrogen receptor modulator that has estrogenic actions on bone and anti-estrogenic actions on the uterus and breast. It is used in the prevention of osteoporosis in postmenopausal women. In 2006, the National Cancer Institute announced that raloxifene was as effective as tamoxifen in reducing the incidence of breast cancer in postmenopausal women at increased risk. A major adverse effect of tamoxifen is uterine cancer; raloxifene had fewer uterine cancers. Tamoxifen increased the risk of cataracts, but raloxifene did not. Both groups had more blood clots in veins and the lungs, but that side effect was more common with tamoxifen than raloxifene. On September 14, 2007, the U.S. Food and Drug Administration announced approval of raloxifene for reducing the risk of invasive breast cancer in postmenopausal women with osteoporosis and in postmenopausal women at high risk for invasive breast cancer. An editorial in Lancet Oncology criticized the way that information about the drug was released.
U.S. National Library of Medicine
A second generation selective estrogen receptor modulator (SERM) used to prevent osteoporosis in postmenopausal women. It has estrogen agonist effects on bone and cholesterol metabolism but behaves as a complete estrogen antagonist on mammary gland and uterine tissue.
The numerical value of raloxifene in Chaldean Numerology is: 6
The numerical value of raloxifene in Pythagorean Numerology is: 1
Sample Sentences & Example Usage
There is now a specific recommendation against using estrogen replacement therapy or raloxifene (Evista) for treatment of osteoporosis in women.
Images & Illustrations of raloxifene
Find a translation for the raloxifene definition in other languages:
Select another language: