Definitions for rabies virus

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  1. Rabies virus

    The rabies virus is a neurotropic virus that causes fatal disease in human and animals. Rabies transmission can occur through the saliva of animals. The rabies virus has a cylindrical morphology and is the type species of the Lyssavirus genus of the Rhabdoviridae family. These viruses are enveloped and have a single stranded RNA genome with negative-sense. The genetic information is packaged as a ribonucleoprotein complex in which RNA is tightly bound by the viral nucleoprotein. The RNA genome of the virus encodes five genes whose order is highly conserved. These genes code for nucleoprotein, phosphoprotein, matrix protein, glycoprotein and the viral RNA polymerase. The complete genome sequences range from 11,615 to11,966 nt in length. All transcription and replication events take place in the cytoplasm inside a specialized “virus factory“, the Negri body. These are 2–10 µm in diameter and are typical for a rabies infection and thus have been used as definite histological proof of such infection.

U.S. National Library of Medicine

  1. Rabies virus

    The type species of LYSSAVIRUS causing rabies in humans and other animals. Transmission is mostly by animal bites through saliva. The virus is neurotropic multiplying in neurons and myotubes of vertebrates.

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