Definitions for rabbit test
This page provides all possible meanings and translations of the word rabbit test
Friedman test, rabbit test(noun)
pregnancy test that involves injecting some of the woman's urine into an unmated female rabbit and later examining the ovaries of the rabbit; presence of corpora lutea indicates that the woman is pregnant
The rabbit test, or Aschheim-Zondek test, was an early pregnancy test developed in 1927 by Bernhard Zondek and Selmar Aschheim. The original test actually used mice, and was based upon the observation that when urine from a female in the early months of pregnancy is injected into immature female mice, the ovaries of the mice enlarge and show follicular maturation. The test was considered reliable, with an error rate of less than 2%. The rabbit test consisted of injecting the tested woman's urine into a female rabbit, then examining the rabbit's ovaries a few days later, which would change in response to a hormone only secreted by pregnant women. The hormone, human chorionic gonadotropin, is produced during pregnancy and indicates the presence of a fertilized egg; it can be found in a pregnant woman's urine and blood. The rabbit test became a widely used bioassay to test for pregnancy. The term "rabbit test" was first recorded in 1949 but became a common phrase in the English language. Xenopus frogs were also used in a similar "frog test". Modern pregnancy tests still operate on the basis of testing for the presence of the hormone hCG. Due to medical advances, use of a live animal is no longer required.
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